| Actor | Main Character | Seasons |
| Sara Mitich | Nilsson | 2 |
| Anthony Rapp | Paul Stamets | |
| Patrick Kwok-Choon | Gen Rhys | |
| Mary Wiseman | Sylvia Tilly | |
| Ronnie Rowe, Jr | R.A. Bryce | |
| Jason Isaacs | Gabriel Lorca | 1 |
| David Ajala | Cleveland "Book" Booker | 3, 4, 5 |
| Shazad Latif | Ash Tyler | 1 |
| Anson Mount | Christopher Pike | 2 |
| Wilson Cruz | Hugh Culber | |
| Callum Keith Rennie | Rayner | 5 |
| Emily Coutts | Keyla Detmer | |
| Oyin Oladejo | Joann Owosekun | |
| Sonequa Martin-Green | Michael Burnham | |
| Sara Mitich | Airiam | 1 |
| Doug Jones | Saru |
| Actor | Character | |
| Simon Northwood | Fred's Guard #1 | 1 |
| Jajube Mandiela | Holo officer #2 | 1 |
| Glen Michael Grant | Delegate | 1 |
| Josh Simpson | Starfleet headquarters officer | 1 |
| Barnaby Carpenter | (voice) ISS Enterprise computer | 1 |
| Anson Mount | (as Pike) Control | 1 |
| Victoria Dunsmore | Alshain female | 1 |
| Katherine Trowell | Captain Bandra | 1 |
| Byron Abalos | Trainee #1 | 1 |
| Ayesha Mansur Gonsalves | J'Vini | 1 |
| Nicole Dickinson | Trial spectator | 1 |
| Amanda Arcuri | Val Sasha | 1 |
| Michelle Browne | Discovery bridge crew | 1 |
| Nicole Dickinson | Hadley | 1 |
| Avaah Blackwell | Osnullus trader | 1 |
| Rothaford Gray | Tareckx | 1 |
| Robert Halley | Silk Dancer | 1 |
| Daniel DeSanto | Kurr's Manager | 1 |
| Shelley Owens | ISS Discovery medical crewmember | 1 |
| Alex Chung | Henchman | 1 |
| JaNae Armogan | Changeling | 1 |
| Fode Bangoura | Alien merchant | 1 |
| Jahkeil Goldson | Science officer | 1 |
| Lisa Berry | Kanak | 1 |
| Karen Robinson | Leader Pav | 1 |
| Gregory Calderone | Lieutenant Jax | 1 |
| Dana Jones | Lord | 1 |
| Joseph Racki | ISS Charon officer | 1 |
| Conrad Pla | Stone | 1 |
| Morgan Kohan | Weapons Trader | 1 |
| Kirk Salesman | Shuttle Klingon 2 | 1 |
| Adam Winlove-Smith | Klingon | 1 |
| Tanu Ravi | Dinner guest #1 | 1 |
| Katherine Barrell | Stella Grimes | 1 |
| Kyana Teresa | CTP Trainee | 1 |
| Mustafa Bulut | Discovery crewman | 1 |
| Michael Boisvert | Kovil | 1 |
| Tim Cody | ISS Shenzhou crewman | 1 |
| Sam Asante | Senior guard | 1 |
| Terry Serpico | Brett Anderson | 1 |
| Chris Zamat | Holo officer #1 | 1 |
| Ingrid Rae Doucet | Moderator | 1 |
| Nicole Dickinson | Talosian #3 | 1 |
| David Benjamin Tomlinson | Young Su'Kal | 1 |
| Mike Dineen | Starfleet headquarters officer | 1 |
| James MacKinnon | Discovery medical technician | 1 |
| Adrian Walters | Cadet Taahz Gorev | 1 |
| Linford Mark Robinson | Captain L'Teis Kardashev | 1 |
| Molly Lewis | Whistlespeaker | 1 |
| Ian James Corlett | (voice) Section 31 computer | 1 |
| Anthony Lake | Ferengi Starfleet Captain | 1 |
| Michelle Browne | Discovery bridge crewmember | 1 |
| Mike Joseph | Credence officer 3 | 1 |
| Jhaleil Swaby | San | 1 |
| David Benjamin Tomlinson | Saurian diplomat | 1 |
| Jón Viðar Arnþórsson | Cardassian henchman | 1 |
| Aldrin Bundoc | Inmate #2 | 1 |
| Jayne Dineo | ISS Discovery sciences crewmember | 1 |
| Angola Murdoch | Silk dancer | 1 |
| Michelle Browne | Discovery bridge crewman | 1 |
| Oksana Sirju | Cashier | 1 |
| Bartell La Rue | Guardian voice | 1 |
| Christopher Allen | Orion guard | 1 |
| J. Adam Brown | Fred | 1 |
| Tig Fong | Lord | 1 |
| Jonathan McGuire | ISS Charon officer | 1 |
| Devon MacDonald | Engineering officer | 1 |
| Anthony Grant | Er'Toom | 1 |
| Dennis Andres | Engineer Rance | 1 |
| Sean Connolly Affleck | Lieutenant Connolly | 1 |
| Simon Northwood | Shuttle pilot | 1 |
| Andrew Moodie | Jacob | 1 |
| Serena Thompson | Vulcan | 1 |
| Jonathan Kim | Albert Kim | 1 |
| David Benjamin Tomlinson | Kelpien villager #1 | 1 |
| Nick Stojanovic | Detmer's date | 1 |
| Maulik Pancholy | Nambue | 1 |
| Lena Banks | (archive image) Romulan officer | 1 |
| Vanessa Burns | Holo security officer #2 | 1 |
| Clare Coulter | Kalzara Bix | 1 |
| Karen Robinson | Pav | 1 |
| Nicole Dickinson | Kili matriarch | 1 |
| Minh Ly | Construction worker | 1 |
| David Sobolov | Ba'ul council member #1 | 1 |
| Antonio Ortega | Engineer | 1 |
| Maria del Mar | (holo) Culber's grandmother | 1 |
| Ali Momen | (as Gant) Control | 1 |
| Katherine Trowell | Starfleet Captain #2 | 1 |
| Phi Huynh | Credence officer 2 | 1 |
| Taylor Martin | Klingon pilot | 1 |
| Tanyta Aquilla Roe | Starfleet diplomat | 1 |
| David Benjamin Tomlinson | Cosmo Traitt | 1 |
| Alireza Shojaei | Inmate #1 | 1 |
| Gloria Belle | ISS Discovery sciences crewmember | 1 |
| Steinar Thors | Andorian henchman | 1 |
| Daniel Kash | Haz Mazaro | 1 |
| John Mucciacito | ISS Discovery engineer | 1 |
| Nick Alachiotis | Henchman | 1 |
| Warren Scherer | Kurr | 1 |
| Daniel Kash | Duggan | 1 |
| Osric Chau | Oros | 1 |
| Danny Waugh | Vulcan holo | 1 |
| Phi Huynh | ISS Charon officer | 1 |
| Grace Lynn Kung | Psycho | 1 |
| Matthew Binkley | Shavo | 1 |
| Sheila McCarthy | Amesha | 1 |
| Nicole Dickinson | Mo'Kai guard #1 | 1 |
| Izaak Smith | Jogger #1 | 1 |
| Mark Pellington | (voice) Ba'ul | 1 |
| Julie St-Louis | Discovery security officer | 1 |
| Sam Vartholomeos | Mirror Danby Connor | 1 |
| Devon MacDonald | Service engineer | 1 |
| Spencer Robson | Terran prisoner #1 | 1 |
| Bobby Brown | Lord | 1 |
| Nicole Nwokolo | FHQ Security officer | 1 |
| RJ Parrish | Holo security officer #1 | 1 |
| Jon De Leon | Section 31 engineer | 1 |
| Farhang Ghajar | Bridge regulator | 1 |
| Derek Chen | Starfleet headquarters doctor | 1 |
| James Cade | Weapons dealer | 1 |
| Jason Anthony | (voice) Control computer | 1 |
| Danijel Mandic | Salvage regulator | 1 |
| Marium Carvell | Anorah | 1 |
| Kenneth Mitchell | Tenavik | 1 |
| Linford Mark Robinson | Starfleet Captain #1 | 1 |
| Vincent Rother | FHQ Security Guard | 1 |
| Victoria Goodman | Credence officer 1 | 1 |
| Kyana Teresa | Doctor | 1 |
| Nck Name | Lieutenant Callum | 1 |
| Sima Sepehri | Lieutenant Adhar | 1 |
| Cait Alexander | ISS Discovery crewmember | 1 |
| Lizz Porter | Ckaptir trader | 1 |
| Kaela Willey | Alien delegate | 1 |
| Adrian Pavone | Ensign Hazmat | 1 |
| Nabel Khatib | Beefy Guy | 1 |
| Mike Tracz | Silk dancer | 1 |
| Christopher Heyerdahl | Wen | 1 |
| Robert Verlaque | Kelpien elder holo | 1 |
| Nicko Giannakos | Tellarite inspector | 1 |
| Mustafa Bulut | ISS Charon officer | 1 |
| Clint Howard | Orion | 1 |
| John MacDonald | Kowski | 1 |
| Steve Gagne | Klingon | 1 |
| Jordan Lockhart | Vulcan | 1 |
| Donovan Brown | Andre Haynes | 1 |
| Ronnie Rowe, Jr | Comm officer 2 | 1 |
| Ana Shepherd | Discovery crewman | 1 |
| Taylor Martin | House of Kor representative | 1 |
| Marcello Bezina | Lord | 1 |
| Bonnie Morgan | Crepuscula | 1 |
| Alexander Mandra | Avryz | 1 |
| Christine Nguyen | Discovery engineer #2 | 1 |
| Addison Holley | Cadet Ross | 1 |
| Wilson Cruz | Jinaal Bix | 1 |
| Alain Chanoine | Regulator escort #1 | 1 |
| Joshua Bainbridge | Regulator | 1 |
| Avaah Blackwell | Kelpien council member #2 | 1 |
| Daniel Jun | Lai | 1 |
| June Laporte | Ravah | 1 |
| Moses Nyarko | Bird-of-Prey Klingon #1 | 1 |
| Anthony Rapp | Holo Paul Stamets | 1 |
| Emmanuel Kabongo | V'Kir | 1 |
| Jason Lee Bell | FHQ Security Guard | 1 |
| Bart Badzioch | Romulan mercenary | 1 |
| Thom Marriott | Council member | 1 |
| Piotr Michael | Shuttle Computer Voice | 1 |
| Jake Michaels | Ithor | 1 |
| Sochi Fried | Akaali Woman | 1 |
| David Benjamin Tomlinson | Kelpien Servant | 1 |
| Bjarki Thor Palsson | Alien henchman | 1 |
| Lizz Porter | Ckaptir delegate | 1 |
| Lindsay Owen Pierre | Os'ir | 1 |
| Jeff Kassel | Referee | 1 |
| Ana Shepherd | Silk dancer | 1 |
| Alain Moussi | Training hologram | 1 |
| Bart Badzioch | ISS Charon officer | 1 |
| Melanie Nicholls-King | Rear Admiral Drake | 1 |
| Elias Toufexis | Cold | 1 |
| Ray Cammaert | Vulcan instructor | 1 |
| Emily Bartlett | Mother in distress | 1 |
| Jonathan Whittaker | Vulcan Director | 1 |
| Pay Chen | Starfleet psychiatrist | 1 |
| Hamza Fouad | Deck crew #2 | 1 |
| Javier Botet | "Old Creature" | 1 |
| Daniel Montlouis | Discovery helmsman | 1 |
| Jenny Itwaru | ISS Shenzhou officer | 1 |
| Marie Ward | Junior guard | 1 |
| Elana Dunkelman | Discovery engineer #1 | 1 |
| Julianne Grossman | (Voice) EV Suit Computer | 1 |
| Patrick Stewart | (archive image) Jean-Luc Picard | 1 |
| Rob Brownstein | The Keeper | 1 |
| Kirpa Budwal | Andorian regulator | 1 |
| Rosie Simon | Starfleet Ensign | 1 |
| Jodi Jahnke | Kelpien council member #1 | 1 |
| Avaah Blackwell | Captain Rahma | 1 |
| Alfredo Narciso | Ohvahz | 1 |
| Nicole Dickinson | Bird-of-Prey Klingon #2 | 1 |
| Donald Olango | Alshain male | 1 |
| Stephanie Belding | Shira | 1 |
| Emmanuel John | FHQ Ops Officer | 1 |
| Leonard Nimoy | Old Spock | 1 |
| Glenn Hetrick | K'Vort | 1 |
| Patrick Haye | Ferin | 1 |
| Brandon McGibbon | Ithyk | 1 |
| Jonathan Goad | Akaali magistrate | 1 |
| Hrólfur Ólafsson | Andorian henchman | 1 |
| Jennifer Chaiet | Alien delegate | 1 |
| Marie A. Irish | Terran Lord | 1 |
| Jonathan Koensgen | Kal | 1 |
| Claudia Jurt | Zakari | 1 |
| Ariana Shaw | Silk dancer | 1 |
| Pamela Mars | Discovery bridge crewman | 1 |
| Lizz Porter | Card dealer | 1 |
| Andrew Hinkson | Regulator | 1 |
| Thamela Mpumlwana | Young T'Kuvma | 1 |
| Harry Judge | Admiral Gorch | 1 |
| Saad Siddiqui | Straal | 1 |
| Bree Wasylenko | Shava | 1 |
| Thai Douchette | Discovery sciences crewmember | 1 |
| Claire Qute | Teen May hologram | 1 |
| Clare McConnell | Dennas | 1 |
| Xavier Sotelo | Captain Diego Vela | 1 |
| Jason Deline | Medical officer | 1 |
| Phi Huynh | Discovery bridge officer | 1 |
| Paulina Miel | Discovery engineering technician #2 | 1 |
| Al Vrkljan | ISS Shenzhou crewman | 1 |
| Kachina Dechert | Terran prisoner #2 | 1 |
| Billy MacLellan | Barlow | 1 |
| Justin Howell | Torchbearer / Rejac | 1 |
| Leatrim Stang | (archive image) Romulan officer | 1 |
| Dee Pelletier | Talosian | 1 |
| Shannon Lahaie | Tactical officer | 1 |
| Rodrigo Fernandez-Stol | Nalas | 1 |
| Kenric Green | Mike Burnham | 1 |
| Jahvonte Morrison | Alshain male | 1 |
| Oliver Becker | N'Raj | 1 |
| Dorian Grey | Breen Lieutenant Arisar | 1 |
| Jennifer Murray | Trainee #3 | 1 |
| Mimi Côté | Qowat Milat Nun | 1 |
| Taylor Martin | Trial spectator | 1 |
| Andrei Kovski | Kwejian hunter 2 | 1 |
| Julianne Grossman | Sanctuary Voice | 1 |
| Sarah Booth | Luda | 1 |
| Gunnar Nelson | Lurian henchman | 1 |
| Nicole Dickinson | Orion Delegate | 1 |
| Kevan Kase | Lookout | 1 |
| Mark Segal | Silk dancer | 1 |
| Dillon Jagersky | Henchman | 1 |
| George Nickolas K. | Alien card player | 1 |
| Nelu Handa | Smiling Starfleet Lieutenant Holo | 1 |
| Xavier Lopez | Passing crew member | 1 |
| Jean-Paul Najm | FHQ security guard | 1 |
| Lamont James | Regulator guard #1 | 1 |
| Michael Copeman | Doctor Vellek | 1 |
| Clayton Scott | Chosen Kelpien slave | 1 |
| David Benjamin Tomlinson | Klingon Player #1 | 1 |
| Jordana Blake | Betarian girl | 1 |
| Nick Alachiotis | Klingon | 1 |
| Kiara Groulx | Rose | 1 |
| Luke Humphrey | V'Latak | 1 |
| Kenneth Mitchell | Kol-Sha | 1 |
| Milton Barnes | Deck crew #1 | 1 |
| Julian Lewis | Discovery crewman | 1 |
| Tyler Evan Webb | Klingon guard | 1 |
| Bart Badzioch | ISS Shenzhou security officer | 1 |
| Maurice Roëves | (archive image) Romulan captain | 1 |
| Melissa George | Vina | 1 |
| Daniel Woodrow | Holo officer #3 | 1 |
| Victor Andrés Trelles Turgeon | Duvin | 1 |
| Pamela Mars | Discovery operations crew member | 1 |
| Golden Madison | Alshain female | 1 |
| Nicole Dickinson | Cardassian captain | 1 |
| Rachael Ancheril | Doctor Nhan | 1 |
| Olivia Croft | Trainee #2 | 1 |
| Khalil Abdul-Malik | Credence first officer | 1 |
| Anthony Lake | Trial spectator | 1 |
| Penande Estime | Kwejian hunter 1 | 1 |
| Michael Greyeyes | Felix | 1 |
| Magnús Ingvarsson | Human henchman | 1 |
| Ivan Lopez | Ensign Cortez | 1 |
| J. Adam Huggins | ISS Discovery engineer | 1 |
| Wole Daramola | Red Eyes (Heavy) | 1 |
| Jason Gosbee | Mat'trub | 1 |
| Martin Samuel | Silk dancer | 1 |
| Jayne Dineo | Discovery sciences crewman | 1 |
| Jennifer Chaiet | Hornish card player | 1 |
| Shawn Campbell | Supervising inspector | 1 |
| Stacey Abrams | President of United Earth | 1 |
| Nicole Dickinson | Strong regulator | 1 |
| Andrew Shaver | Commissioner Vos | 1 |
| Mei Chung | UFP Presidental Aide | 1 |
| Marco Perretta | USS Discovery medical crewman | 1 |
| Julie St-Louis | ISS Charon officer | 1 |
| Ronnie Rowe, Jr | Shuttle pilot | 1 |
| Crystal Leger | Klingon Player #2 | 1 |
| Tyler Evan Webb | Shuttle Klingon 1 | 1 |
| Noah Davis | Lieutenant | 1 |
| Peter MacNeill | Baron Grimes | 1 |
| James Eddy | Discovery crewman | 1 |
| Anthony Grant | Klingon communications officer | 1 |
| Cait Alexander | Discovery bridge crew | 1 |
| Jake Epstein | Doctor Attis | 2 |
| Pamela Mars | Discovery bridge crew member | 2 |
| Ante Dekovic | Kroad | 2 |
| Patrick Kwok-Choon | Mirror Gen Rhys | 2 |
| Tasia Valenza | (voice) ISS Shenzhou computer | 2 |
| Brendan Beiser | Eli | 2 |
| Tony Nappo | Primarch Ruhn | 2 |
| Nicole Dickinson | Yeoman Colt | 2 |
| Paul Guilfoyle | Carl | 2 |
| Michael Chan | FHQ ops officer | 2 |
| Kenneth Welsh | (voice) Senna Tal | 2 |
| Kenneth Mitchell | Aurellio | 2 |
| Dwain Murphy | Captain Maddox | 2 |
| Tara Nicodemo | Admiral Patar | 2 |
| Avaah Blackwell | Osnullus science officer | 2 |
| Chai Valladares | Lieutenant Nicola | 2 |
| Wilson Cruz | Mirror Hugh Culber | 2 |
| David Benjamin Tomlinson | Or'Eq | 2 |
| Hélène Cardona | Discovery engineer | 2 |
| Roy Samuelson | Emerald chain computer | 2 |
| Alex McCooeye | Lee'U | 2 |
| Hanneke Talbot | Lieutenant Mann | 2 |
| Mary Wiseman | Mirror Sylvia Tilly | 2 |
| Pamela Mars | ISS Discovery crewmember | 2 |
| Rainn Wilson | Harcourt Fenton Mudd | 2 |
| Hannah Spear | Siranna | 2 |
| Shazdeh Kapadia | Daughter #2 | 2 |
| Alisen Down | Starfleet psychiatrist | 2 |
| Avaah Blackwell | Osnullus sciences officer | 2 |
| Samora Smallwood | Lieutenant Amin | 2 |
| Doug Jones | Mirror Saru | 2 |
| Greg Leach | Honor guard | 2 |
| Piotr Michael | Shuttle computer | 2 |
| Jinny Jacinto | The Monster | 2 |
| Marco Perretta | Medical officer | 2 |
| Ava MacKinnon | Daughter #1 | 2 |
| Yadira Guevara-Prip | Me Hani Ika Hali Ka Po | 2 |
| Giovanni Spina | Provost Sta'Kiar | 2 |
| Sonequa Martin-Green | Mirror Michael Burnham | 2 |
| Hannah Spear | Doctor Issa | 2 |
| Michelle Browne | Discovery engineer | 2 |
| Michael Ayres | Transporter technician | 2 |
| Ana Sani | Mom | 2 |
| Ian Lake | Tolor | 2 |
| Zarrin Darnell-Martin | Nurse | 2 |
| Adrian Walters | Taahz Gorev | 2 |
| Sara Mitich | Mirror Nilsson | 2 |
| Phi Huynh | Honor guard | 2 |
| Emmanuel John | FHQ security officer | 2 |
| Clare McConnel | Dennas | 2 |
| Michael Ayres | Transport officer | 2 |
| Tyler Hynes | Stephen | 2 |
| Kevin Lee | Enterprise operations crewmember | 2 |
| Seamus Patterson | Harral | 2 |
| Riley Gilchrist | Andorian regulator | 2 |
| Ronnie Rowe, Jr | Mirror R.A. Bryce | 2 |
| Demi Oliver | ISS Shenzhou transporter chief | 2 |
| Jeremy Crittenden | Lord Eling | 2 |
| Sam Vartholomeos | Danby Connor | 2 |
| Pamela Mars | Discovery bridge crew | 3 |
| Jake Weber | Zareh | 3 |
| Bill Irwin | Su'Kal | 3 |
| Salome Jens | (archive images) Ancient humanoid | 3 |
| Adil Hussain | Aditya Sahil | 3 |
| Daniel Montlouis | Discovery security guard | 3 |
| Emily Coutts | Mirror Keyla Detmer | 3 |
| Gloria Belle | Discovery sciences crewmember | 3 |
| Chris Obi | T'Kuvma | 3 |
| Andrew Shiff | Discovery transporter chief | 3 |
| Harry Judge | Admiral Gorch | 3 |
| Javid Iqbal | Voq | 3 |
| Dorren Lee | Lieutenant Teemo | 3 |
| Oyin Oladejo | Mirror Joann Owosekun | 3 |
| Avaah Blackwell | Bridge crewman | 3 |
| Avaah Blackwell | Lieutenant Arav | 3 |
| Daniel Montlouis | Discovery operations crewmember | 3 |
| Shelley Owens | Discovery medical crew member | 3 |
| Christopher Russell | Milton Richter | 3 |
| Noah Averbach-Katz | Ryn | 3 |
| Alan van Sprang | (as Leland) Control | 3 |
| Kenneth Mitchell | Kol | 3 |
| Rebecca Romijn | Una Chin-Riley | 3 |
| Chris Violette | Britch Weeton | 4 |
| Bahia Watson | May Ahearn | 4 |
| Andreas Apergis | Guardian Xi | 4 |
| Tasia Valenza | (voice) Shenzhou computer | 4 |
| George Alevizos | Discovery crewman | 4 |
| Anthony Rapp | Mirror Paul Stamets | 4 |
| Luca Doulgeris | Leto | 4 |
| Conrad Coates | Terral | 4 |
| Christina Dixon | Lieutenant Commander Asha | 4 |
| Janet Kidder | Osyraa | 4 |
| Hiro Kanagawa | Doctor Hirai | 4 |
| Victoria Sawal | Lieutenant Naya | 4 |
| Riley Gilchrist | Rear Admiral Shukar | 4 |
| Ache Hernandez | Kyheem | 4 |
| Damon Runyan | Ujilli | 4 |
| Avaah Blackwell | Lieutenant Ina | 4 |
| Romaine Waite | Troy Januzzi | 4 |
| Natalie Liconti | Lieutenant Gallo | 5 |
| Rekha Sharma | Ellen Landry | 5 |
| Ali Momen | Kamran Gant | 5 |
| Michelle Yeoh | Captain Philippa Georgiou | 5 |
| Vanessa Jackson | Lieutenant Audrey Willa | 5 |
| Phumzile Sitole | General Diatta Ndoye | 6 |
| Sonja Sohn | Gabrielle Burnham | 6 |
| Elias Toufexis | L'ak | 6 |
| Eve Harlow | Moll | 6 |
| Liam Hughes | Young Spock | 6 |
| Alan van Sprang | Leland | 6 |
| Andrea Gallo | Discovery science officer | 7 |
| Hannah Cheesman | Lieutenant Commander Airiam | 7 |
| Ross Carter | Haj | 7 |
| John Mucciacito | Discovery engineer | 7 |
| Shawn Doyle | Ruon Tarka | 8 |
| David Cronenberg | Kovich | 9 |
| Ronald Tang | Discovery engineering technician | 9 |
| Fabio Tassone | (voice) Book's ship computer | 9 |
| James Frain | Sarek | 9 |
| Arista Arhin | Young Michael Burnham | 9 |
| Andrea Gallo | Discovery sciences crewmember | 10 |
| Mia Kirshner | Amanda Grayson | 10 |
| Chelah Horsdal | President Laira Rillak | 11 |
| Jayne Brook | Admiral Katrina Cornwell | 11 |
| Ethan Peck | (voice) Spock | 11 |
| Jayne Dineo | Discovery sciences crewmember | 11 |
| Shelley Owens | Discovery medical crewmember | 11 |
| Blu del Barrio | Adira Tal | 12 |
| Mary Chieffo | L'Rell | 12 |
| Orville Cummings | Lieutenant Christopher | 12 |
| Ian Alexander | Gray Tal | 13 |
| Avaah Blackwell | Osnullus bridge officer | 13 |
| J. Adam Huggins | Discovery engineer | 13 |
| Tara Rosling | President T'Rina | 14 |
| Rachael Ancheril | D. Nhan | 15 |
| Leeu | Grudge | 15 |
| Pamela Mars | Discovery bridge crewmember | 16 |
| Tig Notaro | Jett Reno | 17 |
| Raven Dauda | Doctor Tracy Pollard | 17 |
| Annabelle Wallis | (voice) Zora | 18 |
| Oded Fehr | Charles Vance | 21 |
| Michelle Yeoh | Mirror Philippa Georgiou | 21 |
| David Benjamin Tomlinson | Linus | 24 |
| Julianne Grossman | (voice) Discovery computer | 25 |
| © Graham & Ian Kennedy | Page views : 99,013 | Last updated : 9 Jul 2022 |