| ID | Losses | Type | Description | Episode |
| 35 |
 |
Danube | NCC 72917 USS Mekong was destroyed during the disasterous Romulan / Cardassian attack on the Founder's home world. [1] | The Die is Cast |
| Canon source | Backstage source | Novel source | DITL speculation |
| # | Series | Season | Source | Comment |
| 1 | DS9 | 3 | The Die is Cast |
| Series : | DS9 Season 3 |
| Episode : | The Die is Cast |
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