| Year |
Event |
| 2245 |
| •1 | The first Starship Enterprise is launched from the San Francisco Fleet yards in orbit of Earth.2 The launch is attended by Ex-President of the United Federaton of Planets, Jonathan Archer.3
 |
|
| 2261 |
| •4 | Christine Chapel's fiance, Dr. Roger Korby, disappears on Exo III. His last message describes cave formations he has discovered. Christine gives up a promising career in bioresearch to sign aboard a Starship in order to search for Korby.4
|
|
| 2264 |
| •2 | The Starship Enterprise, under the command of Captain Kirk, is assigned a five year mission of exploration.2
|
|  |
| 2266 |
| •5 | The USS Enterprise destroys a Romulan bird of Prey which has crossed the Neutral Zone and attacked several Federation outposts.5
|
| •6 | Chapel serves aboard the USS Enterprise on this date.6
|
| •7 | While researching a collapsing planet, the crew of the USS Enterprise are incapacitated by a new form of virus. Dr. McCoy is able to overcome the effects of the virus in time to save the ship. In breaking free of the planet, the ship is thrown back several minutes in time - the first known example of time travel by the Federation.7
|
| •6 | The USS Enterprise discovers what appears to be professor Roger Korby alive and well on Exo III. However, it proves to be an android created by ancient technology which Korby discovered on the planet.6
|
|  |
| 2267 |
| •8 | The USS Enterprise arrives at Omicron Seti III. Almost overcome by the effects of the local plant life, the crew manage to break free and rescue the colonists.8
|
|
| 2269 |
| •9 | The USS Enterprise completes its five year mission.9
|
|
| 2270 |
| •10 | The USS Enterprise commences a major refit.10
|
|
| 2271 |
| •11 | Chapel had become an MD by this point.11
|
| •11 | The newly launched USS Enterprise encounters the entity known as V'Ger. V'Ger merges with Commander Decker to become a new life form.11
|
|  |
| 2285 |
| •12 | USS Reliant, searching for a lifeless planet for use in the Genesis experiment, is seized by Khan Noonian Sing. Sing attempts to steal the Genesis Device, but is engaged in battle by the USS Enterprise under the command of Admiral Kirk. Spock is killed saving the Enterprise from destruction.12
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|  |
