| Year |
Event |
| 2227 |
| •1 | McCoy is born on Earth in North America.2
 |
|
| 2244 |
| • | Emony meets Leonard McCoy and has a brief affair with him.3
|
|
| 2245 |
| •4 | The first Starship Enterprise is launched from the San Francisco Fleet yards in orbit of Earth.5 The launch is attended by Ex-President of the United Federaton of Planets, Jonathan Archer.6
|
| •7 | McCoy joins Starfleet medical school.5
|
|
| 2253 |
| •8 | McCoy graduates from Starfleet medical school. He develops an impressive technique for the creation of axonal pathways between grafted neuronal tissue and basal ganglia. This procedure is later incorporated into Starfleet's Emergency Medical Hologram.8
|
|
| 2256 |
| •9 | McCoy ends his romantic involvement with Nancy10
|
|
| 2261 |
| •11 | Robert and Nancy Crater arrive on the planet M113 to do archaeological research.11
|
|  |
| 2264 |
| •5 | The Starship Enterprise, under the command of Captain Kirk, is assigned a five year mission of exploration.5
|
| •11 | Nancy Crater is killed on planet M113 by a creature native to the planet. The creature, which is able to assume any appearance it chooses, lives with Professor Crater.11
|
|  |
| 2266 |
| •12 | The USS Enterprise destroys a Romulan bird of Prey which has crossed the Neutral Zone and attacked several Federation outposts.12
|
| •13 | McCoy is assigned as chief medical officer of the USS Enterprise.14
|
| •11 | The USS Enterprise visits M113 on a routine stop. Several crew members are killed by a creature native to the planet which has been living in the guise of Nancy Crater.11
|
| •15 | While researching a collapsing planet, the crew of the USS Enterprise are incapacitated by a new form of virus. Dr. McCoy is able to overcome the effects of the virus in time to save the ship. In breaking free of the planet, the ship is thrown back several minutes in time - the first known example of time travel by the Federation.15
|
|  |
| 2267 |
| •16 | The USS Enterprise is researching Murusaki-312, a quasar-like phenomena, when the shuttlecraft Galileo is lost on the planet Taurus II. The shuttle is able to regain suborbital height long enough to the surviving crew be retrieved by the departing Enterprise.16
|
| •17 | The USS Enterprise arrives at Omicron Seti III. Almost overcome by the effects of the local plant life, the crew manage to break free and rescue the colonists.17
|
|
| 2269 |
| •18 | The USS Enterprise completes its five year mission.18
|
|
| 2270 |
| •19 | McCoy retires from Starfleet.20
|
| •21 | The USS Enterprise commences a major refit.21
|
|
| 2271 |
| •20 | McCoy is drafted back into Starfleet against his wishes under the little-known, seldom-used 'reserve activation clause'.20
|
| •20 | The newly launched USS Enterprise encounters the entity known as V'Ger. V'Ger merges with Commander Decker to become a new life form.20
|
|  |
| 2277 |
| •22 | McCoy is promoted to Commander.22
|
|
| 2285 |
| •23 | USS Reliant, searching for a lifeless planet for use in the Genesis experiment, is seized by Khan Noonian Sing. Sing attempts to steal the Genesis Device, but is engaged in battle by the USS Enterprise under the command of Admiral Kirk. Spock is killed saving the Enterprise from destruction.23
|
|  |
| 2293 |
| •24 | The Enterprise-A escorts Chancellor Gorkon to Earth for a peace conference. When Gorkon is assassinated, Kirk uncovers a plot to reverse the recent easing of tensions between the Federation and Klingons.24
|
| •24 | The Enterprise-A crew are responsible for saving the Khitomer Peace Conference, along with Captain Sulu of the USS Excelsior.24
|
| •25 | The Enterprise-A is decommissioned.25
|
| •24 | McCoy retires from Starfleet.24
|
|  |
| 2300 |
| • | McCoy returns to Starfleet.1
|
|
| 2364 |
| •1 | Admiral McCoy makes an inspection of the Enterprise-D during her maiden voyage.1
|
|
