I like my sig for funny. as well as:
"I protest! I am NOT and MERRY MAN!" - Worf
Anything and everything Morn ever said (off camera of course...)
And then, of cousre, there this:
Kirk: Khan, you bloodsucker. You're going to have to do your own dirty work now! Do you hear me? Do you?
Khan: Kirk? You're still alive, my old friend?
Kirk: Still, "old friend!" You've managed to kill everyone else, but like a poor marksman, you keep missing the target!
Khan: Perhaps I no longer need to try, Admiral.
[beams the Genesis device away]
Kirk: Khan... Khan, you've got Genesis, but you don't have me. You were going to kill me, Khan. You're going to have to come down here. You're going to have to come down here!
Khan: I've done far worse than kill you, Admiral. I've hurt you. And I wish to go on hurting you. I shall leave you as you left me, as you left her; marooned for all eternity in the center of a dead planet... buried alive! Buried alive...!